Which organism is associated with immunodeficiency syndromes and melioidosis?

The organism associated with immunodeficiency syndromes and melioidosis is Burkholderia pseudomallei. This bacterium is the causative agent of melioidosis, a disease that can lead to severe infections, particularly in individuals who are immunocompromised or have underlying health conditions such as diabetes. Melioidosis can present with a variety of clinical manifestations, ranging from localized skin infections to severe pneumonia and sepsis.

Burkholderia pseudomallei is notable for its ability to persist in the environment, especially in tropical and subtropical regions, and can be transmitted through contaminated water or soil. Its role in immunodeficiency syndromes highlights the increased risk that these patients face when exposed to this pathogen, making it a significant concern in clinical microbiology and infectious disease.

Other choices, while significant in their own right, do not have the same association with immunocompromised conditions and melioidosis specifically. Thus, the focus on Burkholderia pseudomallei underscores its clinical importance in both melioidosis and its impact on immunocompromised individuals.